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authorAaron M. Ucko <ucko@debian.org>2005-03-23 15:50:17 +0000
committerAaron M. Ucko <ucko@debian.org>2005-03-23 15:50:17 +0000
commit5d9c18cdc6c0e622f123be548f6f7b8ba827d3ac (patch)
tree2b219ac945a1f81c6a6ffc09fa0db76191716644 /asn/seq.asn
[svn-inject] Installing original source of ncbi-tools6 (6.0.2)
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+--$Revision: 6.0 $
+--**********************************************************************
+--
+-- NCBI Sequence elements
+-- by James Ostell, 1990
+-- Version 3.0 - June 1994
+--
+--**********************************************************************
+
+NCBI-Sequence DEFINITIONS ::=
+BEGIN
+
+EXPORTS Bioseq, Seq-annot, Pubdesc, Seq-descr, Seqdesc, Numbering, Heterogen,
+ Seq-hist;
+
+IMPORTS Date, Int-fuzz, Dbtag, Object-id, User-object FROM NCBI-General
+ Seq-align FROM NCBI-Seqalign
+ Seq-feat FROM NCBI-Seqfeat
+ Seq-graph FROM NCBI-Seqres
+ Pub-equiv FROM NCBI-Pub
+ Org-ref FROM NCBI-Organism
+ BioSource FROM NCBI-BioSource
+ Seq-id, Seq-loc FROM NCBI-Seqloc
+ GB-block FROM GenBank-General
+ PIR-block FROM PIR-General
+ EMBL-block FROM EMBL-General
+ SP-block FROM SP-General
+ PRF-block FROM PRF-General
+ PDB-block FROM PDB-General;
+
+--*** Sequence ********************************
+--*
+
+Bioseq ::= SEQUENCE {
+ id SET OF Seq-id , -- equivalent identifiers
+ descr Seq-descr OPTIONAL , -- descriptors
+ inst Seq-inst , -- the sequence data
+ annot SET OF Seq-annot OPTIONAL }
+
+--*** Descriptors *****************************
+--*
+
+Seq-descr ::= SET OF Seqdesc
+
+Seqdesc ::= CHOICE {
+ mol-type GIBB-mol , -- type of molecule
+ modif SET OF GIBB-mod , -- modifiers
+ method GIBB-method , -- sequencing method
+ name VisibleString , -- a name for this sequence
+ title VisibleString , -- a title for this sequence
+ org Org-ref , -- if all from one organism
+ comment VisibleString , -- a more extensive comment
+ num Numbering , -- a numbering system
+ maploc Dbtag , -- map location of this sequence
+ pir PIR-block , -- PIR specific info
+ genbank GB-block , -- GenBank specific info
+ pub Pubdesc , -- a reference to the publication
+ region VisibleString , -- overall region (globin locus)
+ user User-object , -- user defined object
+ sp SP-block , -- SWISSPROT specific info
+ dbxref Dbtag , -- xref to other databases
+ embl EMBL-block , -- EMBL specific information
+ create-date Date , -- date entry first created/released
+ update-date Date , -- date of last update
+ prf PRF-block , -- PRF specific information
+ pdb PDB-block , -- PDB specific information
+ het Heterogen , -- cofactor, etc associated but not bound
+ source BioSource , -- source of materials, includes Org-ref
+ molinfo MolInfo } -- info on the molecule and techniques
+
+--******* NOTE:
+--* mol-type, modif, method, and org are consolidated and expanded
+--* in Org-ref, BioSource, and MolInfo in this specification. They
+--* will be removed in later specifications. Do not use them in the
+--* the future. Instead expect the new structures.
+--*
+--***************************
+
+--********************************************************************
+--
+-- MolInfo gives information on the
+-- classification of the type and quality of the sequence
+--
+-- WARNING: this will replace GIBB-mol, GIBB-mod, GIBB-method
+--
+--********************************************************************
+
+MolInfo ::= SEQUENCE {
+ biomol INTEGER {
+ unknown (0) ,
+ genomic (1) ,
+ pre-RNA (2) , -- precursor RNA of any sort really
+ mRNA (3) ,
+ rRNA (4) ,
+ tRNA (5) ,
+ snRNA (6) ,
+ scRNA (7) ,
+ peptide (8) ,
+ other-genetic (9) , -- other genetic material
+ genomic-mRNA (10) , -- reported a mix of genomic and cdna sequence
+ other (255) } DEFAULT unknown ,
+ tech INTEGER {
+ unknown (0) ,
+ standard (1) , -- standard sequencing
+ est (2) , -- Expressed Sequence Tag
+ sts (3) , -- Sequence Tagged Site
+ survey (4) , -- one-pass genomic sequence
+ genemap (5) , -- from genetic mapping techniques
+ physmap (6) , -- from physical mapping techniques
+ derived (7) , -- derived from other data, not a primary entity
+ concept-trans (8) , -- conceptual translation
+ seq-pept (9) , -- peptide was sequenced
+ both (10) , -- concept transl. w/ partial pept. seq.
+ seq-pept-overlap (11) , -- sequenced peptide, ordered by overlap
+ seq-pept-homol (12) , -- sequenced peptide, ordered by homology
+ concept-trans-a (13) , -- conceptual transl. supplied by author
+ htgs-1 (14) , -- unordered High Throughput sequence contig
+ htgs-2 (15) , -- ordered High Throughput sequence contig
+ htgs-3 (16) , -- finished High Throughput sequence
+ other (255) } -- use Source.techexp
+ DEFAULT unknown ,
+ techexp VisibleString OPTIONAL , -- explanation if tech not enough
+ completeness INTEGER {
+ unknown (0) ,
+ complete (1) , -- complete biological entity
+ partial (2) , -- partial but no details given
+ no-left (3), -- missing 5' or NH3 end
+ no-right (4) , -- missing 3' or COOH end
+ no-ends (5) , -- missing both ends
+ other (255) } DEFAULT unknown }
+
+
+GIBB-mol ::= ENUMERATED { -- type of molecule represented
+ unknown (0) ,
+ genomic (1) ,
+ pre-mRNA (2) , -- precursor RNA of any sort really
+ mRNA (3) ,
+ rRNA (4) ,
+ tRNA (5) ,
+ snRNA (6) ,
+ scRNA (7) ,
+ peptide (8) ,
+ other-genetic (9) , -- other genetic material
+ genomic-mRNA (10) , -- reported a mix of genomic and cdna sequence
+ other (255) }
+
+GIBB-mod ::= ENUMERATED { -- GenInfo Backbone modifiers
+ dna (0) ,
+ rna (1) ,
+ extrachrom (2) ,
+ plasmid (3) ,
+ mitochondrial (4) ,
+ chloroplast (5) ,
+ kinetoplast (6) ,
+ cyanelle (7) ,
+ synthetic (8) ,
+ recombinant (9) ,
+ partial (10) ,
+ complete (11) ,
+ mutagen (12) , -- subject of mutagenesis ?
+ natmut (13) , -- natural mutant ?
+ transposon (14) ,
+ insertion-seq (15) ,
+ no-left (16) , -- missing left end (5' for na, NH2 for aa)
+ no-right (17) , -- missing right end (3' or COOH)
+ macronuclear (18) ,
+ proviral (19) ,
+ est (20) , -- expressed sequence tag
+ sts (21) , -- sequence tagged site
+ survey (22) , -- one pass survey sequence
+ chromoplast (23) ,
+ genemap (24) , -- is a genetic map
+ restmap (25) , -- is an ordered restriction map
+ physmap (26) , -- is a physical map (not ordered restriction map)
+ other (255) }
+
+GIBB-method ::= ENUMERATED { -- sequencing methods
+ concept-trans (1) , -- conceptual translation
+ seq-pept (2) , -- peptide was sequenced
+ both (3) , -- concept transl. w/ partial pept. seq.
+ seq-pept-overlap (4) , -- sequenced peptide, ordered by overlap
+ seq-pept-homol (5) , -- sequenced peptide, ordered by homology
+ concept-trans-a (6) , -- conceptual transl. supplied by author
+ other (255) }
+
+Numbering ::= CHOICE { -- any display numbering system
+ cont Num-cont , -- continuous numbering
+ enum Num-enum , -- enumerated names for residues
+ ref Num-ref , -- by reference to another sequence
+ real Num-real } -- supports mapping to a float system
+
+Num-cont ::= SEQUENCE { -- continuous display numbering system
+ refnum INTEGER DEFAULT 1, -- number assigned to first residue
+ has-zero BOOLEAN DEFAULT FALSE , -- 0 used?
+ ascending BOOLEAN DEFAULT TRUE } -- ascending numbers?
+
+Num-enum ::= SEQUENCE { -- any tags to residues
+ num INTEGER , -- number of tags to follow
+ names SEQUENCE OF VisibleString } -- the tags
+
+Num-ref ::= SEQUENCE { -- by reference to other sequences
+ type ENUMERATED { -- type of reference
+ not-set (0) ,
+ sources (1) , -- by segmented or const seq sources
+ aligns (2) } , -- by alignments given below
+ aligns Seq-align OPTIONAL }
+
+Num-real ::= SEQUENCE { -- mapping to floating point system
+ a REAL , -- from an integer system used by Bioseq
+ b REAL , -- position = (a * int_position) + b
+ units VisibleString OPTIONAL }
+
+Pubdesc ::= SEQUENCE { -- how sequence presented in pub
+ pub Pub-equiv , -- the citation(s)
+ name VisibleString OPTIONAL , -- name used in paper
+ fig VisibleString OPTIONAL , -- figure in paper
+ num Numbering OPTIONAL , -- numbering from paper
+ numexc BOOLEAN OPTIONAL , -- numbering problem with paper
+ poly-a BOOLEAN OPTIONAL , -- poly A tail indicated in figure?
+ maploc VisibleString OPTIONAL , -- map location reported in paper
+ seq-raw StringStore OPTIONAL , -- original sequence from paper
+ align-group INTEGER OPTIONAL , -- this seq aligned with others in paper
+ comment VisibleString OPTIONAL, -- any comment on this pub in context
+ reftype INTEGER { -- type of reference in a GenBank record
+ seq (0) , -- refers to sequence
+ sites (1) , -- refers to unspecified features
+ feats (2) } DEFAULT seq } -- refers to specified features
+
+Heterogen ::= VisibleString -- cofactor, prosthetic group, inibitor, etc
+
+--*** Instances of sequences *******************************
+--*
+
+Seq-inst ::= SEQUENCE { -- the sequence data itself
+ repr ENUMERATED { -- representation class
+ not-set (0) , -- empty
+ virtual (1) , -- no seq data
+ raw (2) , -- continuous sequence
+ seg (3) , -- segmented sequence
+ const (4) , -- constructed sequence
+ ref (5) , -- reference to another sequence
+ consen (6) , -- consensus sequence or pattern
+ map (7) , -- ordered map of any kind
+ delta (8) , -- sequence made by changes (delta) to others
+ other (255) } ,
+ mol ENUMERATED { -- molecule class in living organism
+ not-set (0) , -- > cdna = rna
+ dna (1) ,
+ rna (2) ,
+ aa (3) ,
+ na (4) , -- just a nucleic acid
+ other (255) } ,
+ length INTEGER OPTIONAL , -- length of sequence in residues
+ fuzz Int-fuzz OPTIONAL , -- length uncertainty
+ topology ENUMERATED { -- topology of molecule
+ not-set (0) ,
+ linear (1) ,
+ circular (2) ,
+ tandem (3) , -- some part of tandem repeat
+ other (255) } DEFAULT linear ,
+ strand ENUMERATED { -- strandedness in living organism
+ not-set (0) ,
+ ss (1) , -- single strand
+ ds (2) , -- double strand
+ mixed (3) ,
+ other (255) } OPTIONAL , -- default ds for DNA, ss for RNA, pept
+ seq-data Seq-data OPTIONAL , -- the sequence
+ ext Seq-ext OPTIONAL , -- extensions for special types
+ hist Seq-hist OPTIONAL } -- sequence history
+
+--*** Sequence Extensions **********************************
+--* for representing more complex types
+--* const type uses Seq-hist.assembly
+
+Seq-ext ::= CHOICE {
+ seg Seg-ext , -- segmented sequences
+ ref Ref-ext , -- hot link to another sequence (a view)
+ map Map-ext , -- ordered map of markers
+ delta Delta-ext }
+
+Seg-ext ::= SEQUENCE OF Seq-loc
+
+Ref-ext ::= Seq-loc
+
+Map-ext ::= SEQUENCE OF Seq-feat
+
+Delta-ext ::= SEQUENCE OF Delta-seq
+
+Delta-seq ::= CHOICE {
+ loc Seq-loc , -- point to a sequence
+ literal Seq-literal } -- a piece of sequence
+
+Seq-literal ::= SEQUENCE {
+ length INTEGER , -- must give a length in residues
+ fuzz Int-fuzz OPTIONAL , -- could be unsure
+ seq-data Seq-data OPTIONAL } -- may have the data
+
+--*** Sequence History Record ***********************************
+--** assembly = records how seq was assembled from others
+--** replaces = records sequences made obsolete by this one
+--** replaced-by = this seq is made obsolete by another(s)
+
+Seq-hist ::= SEQUENCE {
+ assembly SET OF Seq-align OPTIONAL ,-- how was this assembled?
+ replaces Seq-hist-rec OPTIONAL , -- seq makes these seqs obsolete
+ replaced-by Seq-hist-rec OPTIONAL , -- these seqs make this one obsolete
+ deleted CHOICE {
+ bool BOOLEAN ,
+ date Date } OPTIONAL }
+
+Seq-hist-rec ::= SEQUENCE {
+ date Date OPTIONAL ,
+ ids SET OF Seq-id }
+
+--*** Various internal sequence representations ************
+--* all are controlled, fixed length forms
+
+Seq-data ::= CHOICE { -- sequence representations
+ iupacna IUPACna , -- IUPAC 1 letter nuc acid code
+ iupacaa IUPACaa , -- IUPAC 1 letter amino acid code
+ ncbi2na NCBI2na , -- 2 bit nucleic acid code
+ ncbi4na NCBI4na , -- 4 bit nucleic acid code
+ ncbi8na NCBI8na , -- 8 bit extended nucleic acid code
+ ncbipna NCBIpna , -- nucleic acid probabilities
+ ncbi8aa NCBI8aa , -- 8 bit extended amino acid codes
+ ncbieaa NCBIeaa , -- extended ASCII 1 letter aa codes
+ ncbipaa NCBIpaa , -- amino acid probabilities
+ ncbistdaa NCBIstdaa } -- consecutive codes for std aas
+
+
+IUPACna ::= StringStore -- IUPAC 1 letter codes, no spaces
+IUPACaa ::= StringStore -- IUPAC 1 letter codes, no spaces
+NCBI2na ::= OCTET STRING -- 00=A, 01=C, 10=G, 11=T
+NCBI4na ::= OCTET STRING -- 1 bit each for agct
+ -- 0001=A, 0010=C, 0100=G, 1000=T/U
+ -- 0101=Purine, 1010=Pyrimidine, etc
+NCBI8na ::= OCTET STRING -- for modified nucleic acids
+NCBIpna ::= OCTET STRING -- 5 octets/base, prob for a,c,g,t,n
+ -- probabilities are coded 0-255 = 0.0-1.0
+NCBI8aa ::= OCTET STRING -- for modified amino acids
+NCBIeaa ::= StringStore -- ASCII extended 1 letter aa codes
+ -- IUPAC codes + U=selenocysteine
+NCBIpaa ::= OCTET STRING -- 25 octets/aa, prob for IUPAC aas in order:
+ -- A-Y,B,Z,X,(ter),anything
+ -- probabilities are coded 0-255 = 0.0-1.0
+NCBIstdaa ::= OCTET STRING -- codes 0-25, 1 per byte
+
+--*** Sequence Annotation *************************************
+--*
+
+Annot-id ::= CHOICE {
+ local Object-id ,
+ ncbi INTEGER ,
+ general Dbtag }
+
+Annot-descr ::= SET OF Annotdesc
+
+Annotdesc ::= CHOICE {
+ name VisibleString , -- a short name for this collection
+ title VisibleString , -- a title for this collection
+ comment VisibleString , -- a more extensive comment
+ pub Pubdesc , -- a reference to the publication
+ user User-object , -- user defined object
+ create-date Date , -- date entry first created/released
+ update-date Date , -- date of last update
+ src Seq-id , -- source sequence from which annot came
+ align Align-def, -- definition of the SeqAligns
+ region Seq-loc } -- all contents cover this region
+
+Align-def ::= SEQUENCE {
+ align-type INTEGER { -- class of align Seq-annot
+ ref (1) , -- set of alignments to the same sequence
+ alt (2) , -- set of alternate alignments of the same seqs
+ blocks (3) , -- set of aligned blocks in the same seqs
+ other (255) } ,
+ ids SET OF Seq-id OPTIONAL } -- used for the one ref seqid for now
+
+Seq-annot ::= SEQUENCE {
+ id SET OF Annot-id OPTIONAL ,
+ db INTEGER { -- source of annotation
+ genbank (1) ,
+ embl (2) ,
+ ddbj (3) ,
+ pir (4) ,
+ sp (5) ,
+ bbone (6) ,
+ pdb (7) ,
+ other (255) } OPTIONAL ,
+ name VisibleString OPTIONAL ,-- source if "other" above
+ desc Annot-descr OPTIONAL , -- used only for stand alone Seq-annots
+ data CHOICE {
+ ftable SET OF Seq-feat ,
+ align SET OF Seq-align ,
+ graph SET OF Seq-graph ,
+ ids SET OF Seq-id , -- used for communication between tools
+ locs SET OF Seq-loc } } -- used for communication between tools
+
+END
+
+